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Pfizer vs UnitedHealth Group: Business Model & Financial Comparison 2026

Pfizer · Healthcare / Drug Manufacturers - General·UnitedHealth Group · Healthcare / Healthcare Plans

Financial Comparison

MetricPFEPfizerUNHUnitedHealth Group
Market Cap$152.73B$251.47B
Revenue (TTM)$62.58B$447.57B
Revenue Growth-1.2%12.3%
Gross Margin75.8%18.5%
Operating Margin23.9%0.3%
Net Margin12.4%2.7%
Return on Equity8.9%12.5%
P/E (Trailing)19.8x20.9x
P/E (Forward)9.5x13.9x
Free Cash Flow$13.43B$13.86B
Cash$13.60B$28.12B
Total Debt$67.65B$83.00B

Data sourced from Yahoo Finance. Green highlights indicate better performance for that metric. Use the interactive tool for real-time data.

Business Model Comparison

Pfizer

Pfizer Inc. stands as a leading company in Healthcare. Generating $62.58 billion in annual revenue (growing -1.2% year-over-year) and carrying a market capitalization of $151.30 billion, the company has cemented its position as a foundational player in the global Drug Manufacturers - General landscape. Under the leadership of its leadership team, Pfizer Inc. continues to execute on a multi-year strategic vision that balances growth investment wit…

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UnitedHealth Group

UnitedHealth Group Incorporated stands as a leading company in Healthcare. Generating $447.57 billion in annual revenue (growing 12.3% year-over-year) and carrying a market capitalization of $261.58 billion, the company has cemented its position as a foundational player in the global Healthcare Plans landscape. Under the leadership of its leadership team, UnitedHealth Group Incorporated continues to execute on a multi-year strategic vision that b…

Full UnitedHealth Group analysis →

SWOT Analysis Comparison

Strengths
Pfizer
  • With a market capitalization of $151.30B, Pfizer Inc. is one of the largest companies in its sector, providing the scale advantages of brand recognition, supplier leverage, and capital access that sma
  • Pfizer Inc.'s gross margin of 75.8% is well above industry averages, reflecting pricing power, operational efficiency, or a high-value product mix. The operating margin of 23.9% demonstrates disciplin
  • Pfizer Inc. generated $13.43B in free cash flow, providing financial flexibility to invest in growth initiatives, return capital to shareholders, or strengthen the balance sheet.
UnitedHealth Group
  • With a market capitalization of $261.58B, UnitedHealth Group Incorporated is one of the largest companies in its sector, providing the scale advantages of brand recognition, supplier leverage, and cap
  • Revenue grew 12.3% year-over-year to $447.57B, indicating strong demand for UnitedHealth Group Incorporated's products and services and outperformance relative to many industry peers.
  • UnitedHealth Group Incorporated generated $13.86B in free cash flow, providing financial flexibility to invest in growth initiatives, return capital to shareholders, or strengthen the balance sheet.
Weaknesses
Pfizer
  • Pfizer Inc.'s debt-to-equity ratio of 78.0 indicates meaningful financial leverage. Total debt stands at $67.65B against $13.60B in cash and equivalents.
  • Year-over-year revenue declined 1.2%, raising questions about demand for Pfizer Inc.'s core offerings and requiring management to articulate a credible recovery path.
UnitedHealth Group
  • UnitedHealth Group Incorporated's debt-to-equity ratio of 81.6 indicates meaningful financial leverage. Total debt stands at $83.00B against $28.12B in cash and equivalents.
  • A net profit margin of 2.7% leaves limited buffer against revenue fluctuations or cost increases. Any significant market downturn could quickly pressure profitability.
  • With 390,000 employees globally, UnitedHealth Group Incorporated faces inherent challenges in agility, decision-making speed, and maintaining a consistent culture across geographies — advantages that
Opportunities
Pfizer
  • Pfizer Inc. operates in the Drug Manufacturers - General segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in this env
  • Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for Pfizer
  • With $13.60B in cash and strong free cash flow generation, Pfizer Inc. is well-positioned to pursue strategic acquisitions that expand its capabilities, customer base, or geographic reach.
UnitedHealth Group
  • UnitedHealth Group Incorporated operates in the Healthcare Plans segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in
  • Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for UnitedH
  • With $28.12B in cash and strong free cash flow generation, UnitedHealth Group Incorporated is well-positioned to pursue strategic acquisitions that expand its capabilities, customer base, or geographi
Threats
Pfizer
  • Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. Pfizer Inc.'s revenue is not fully insulated from macroeconomic cycles, and a recession scen
  • Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on Pfizer Inc.'s busin
  • Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri
UnitedHealth Group
  • Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. UnitedHealth Group Incorporated's revenue is not fully insulated from macroeconomic cycles,
  • Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on UnitedHealth Group
  • Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri

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Pfizer vs UnitedHealth Group: FAQ

Is Pfizer bigger than UnitedHealth Group?
By market capitalization, UnitedHealth Group is larger at $251.47B vs Pfizer's $152.73B.
Which has better profit margins — Pfizer or UnitedHealth Group?
Pfizer has higher net profit margins (12.4%) compared to UnitedHealth Group (2.7%). Gross and operating margins are compared in the table above.
What sectors do Pfizer and UnitedHealth Group operate in?
Pfizer operates in the Healthcare sector (Drug Manufacturers - General). UnitedHealth Group operates in the Healthcare sector (Healthcare Plans).
How does Pfizer's revenue compare to UnitedHealth Group's?
Pfizer generates $62.58B in annual revenue (TTM) while UnitedHealth Group generates $447.57B. UnitedHealth Group is the larger company by revenue as of 2026.