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Johnson & Johnson vs Moderna: Business Model & Financial Comparison 2026

Johnson & Johnson · Healthcare / Drug Manufacturers - General·Moderna · Healthcare / Biotechnology

Financial Comparison

MetricJNJJohnson & JohnsonMRNAModerna
Market Cap$582.04B$20.76B
Revenue (TTM)$94.19B$1.94B
Revenue Growth9.1%-29.8%
Gross Margin68.1%-105.8%
Operating Margin24.0%-126.4%
Net Margin28.5%-145.2%
Return on Equity35.0%-28.9%
P/E (Trailing)21.9xN/A
P/E (Forward)19.2x-11.5x
Free Cash Flow$16.63B$-1.33B
Cash$20.10B$5.80B
Total Debt$49.33B$1.30B

Data sourced from Yahoo Finance. Green highlights indicate better performance for that metric. Use the interactive tool for real-time data.

Business Model Comparison

Johnson & Johnson

Johnson & Johnson stands as a leading company in Healthcare. Generating $94.19 billion in annual revenue (growing 9.1% year-over-year) and carrying a market capitalization of $577.48 billion, the company has cemented its position as a foundational player in the global Drug Manufacturers - General landscape. Under the leadership of its leadership team, Johnson & Johnson continues to execute on a multi-year strategic vision that balances growth inv…

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Moderna

Moderna, Inc. stands as a leading company in Healthcare. Generating $1.94 billion in annual revenue (growing -29.8% year-over-year) and carrying a market capitalization of $21.26 billion, the company has cemented its position as a foundational player in the global Biotechnology landscape. Under the leadership of its leadership team, Moderna, Inc. continues to execute on a multi-year strategic vision that balances growth investment with shareholde…

Full Moderna analysis →

SWOT Analysis Comparison

Strengths
Johnson & Johnson
  • With a market capitalization of $577.48B, Johnson & Johnson is one of the largest companies in its sector, providing the scale advantages of brand recognition, supplier leverage, and capital access th
  • Johnson & Johnson's gross margin of 68.1% is well above industry averages, reflecting pricing power, operational efficiency, or a high-value product mix. The operating margin of 24.0% demonstrates dis
  • A return on equity of 35.0% demonstrates that Johnson & Johnson generates strong returns from shareholder capital, a hallmark of companies with durable competitive advantages.
Moderna
  • Moderna, Inc. holds an established position in the Biotechnology sector, with a track record of serving customers and generating value across its core business activities.
  • The company's deep expertise in Biotechnology — developed over years of operation — provides meaningful barriers to entry and customer relationship advantages that newer competitors must overcome.
Weaknesses
Johnson & Johnson
  • Johnson & Johnson's debt-to-equity ratio of 60.5 indicates meaningful financial leverage. Total debt stands at $49.33B against $20.10B in cash and equivalents.
  • With 138,200 employees globally, Johnson & Johnson faces inherent challenges in agility, decision-making speed, and maintaining a consistent culture across geographies — advantages that smaller, nimbl
Moderna
  • Year-over-year revenue declined 29.8%, raising questions about demand for Moderna, Inc.'s core offerings and requiring management to articulate a credible recovery path.
Opportunities
Johnson & Johnson
  • Johnson & Johnson operates in the Drug Manufacturers - General segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in th
  • Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for Johnson
  • Earnings growth of 48.6% YoY demonstrates Johnson & Johnson's ability to convert revenue growth into shareholder value. Analysts project continued earnings expansion driven by operating leverage as fi
Moderna
  • Moderna, Inc. operates in the Biotechnology segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in this environment tran
  • Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for Moderna
  • With $5.80B in cash and strong free cash flow generation, Moderna, Inc. is well-positioned to pursue strategic acquisitions that expand its capabilities, customer base, or geographic reach.
Threats
Johnson & Johnson
  • Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. Johnson & Johnson's revenue is not fully insulated from macroeconomic cycles, and a recessio
  • Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on Johnson & Johnson's
  • Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri
Moderna
  • Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. Moderna, Inc.'s revenue is not fully insulated from macroeconomic cycles, and a recession sc
  • Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on Moderna, Inc.'s bus
  • Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri

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Johnson & Johnson vs Moderna: FAQ

Is Johnson & Johnson bigger than Moderna?
By market capitalization, Johnson & Johnson is larger at $582.04B vs Moderna's $20.76B.
Which has better profit margins — Johnson & Johnson or Moderna?
Johnson & Johnson has higher net profit margins (28.5%) compared to Moderna (-145.2%). Gross and operating margins are compared in the table above.
What sectors do Johnson & Johnson and Moderna operate in?
Johnson & Johnson operates in the Healthcare sector (Drug Manufacturers - General). Moderna operates in the Healthcare sector (Biotechnology).
How does Johnson & Johnson's revenue compare to Moderna's?
Johnson & Johnson generates $94.19B in annual revenue (TTM) while Moderna generates $1.94B. Johnson & Johnson is the larger company by revenue as of 2026.

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