Amgen vs UnitedHealth Group: Business Model & Financial Comparison 2026
Amgen · Healthcare / Drug Manufacturers - General·UnitedHealth Group · Healthcare / Healthcare Plans
Financial Comparison
| Metric | AMGNAmgen | UNHUnitedHealth Group |
|---|---|---|
| Market Cap | $198.26B | $251.47B |
| Revenue (TTM) | $36.75B | $447.57B |
| Revenue Growth | 8.6% | 12.3% |
| Gross Margin | 70.8% | 18.5% |
| Operating Margin | 30.5% | 0.3% |
| Net Margin | 21.0% | 2.7% |
| Return on Equity | 106.1% | 12.5% |
| P/E (Trailing) | 25.8x | 20.9x |
| P/E (Forward) | 15.8x | 13.9x |
| Free Cash Flow | $7.50B | $13.86B |
| Cash | $9.13B | $28.12B |
| Total Debt | $55.44B | $83.00B |
Data sourced from Yahoo Finance. Green highlights indicate better performance for that metric. Use the interactive tool for real-time data.
Business Model Comparison
Amgen
Amgen Inc. stands as a leading company in Healthcare. Generating $36.75 billion in annual revenue (growing 8.6% year-over-year) and carrying a market capitalization of $198.16 billion, the company has cemented its position as a foundational player in the global Drug Manufacturers - General landscape. Under the leadership of its leadership team, Amgen Inc. continues to execute on a multi-year strategic vision that balances growth investment with s…
Full Amgen analysis →UnitedHealth Group
UnitedHealth Group Incorporated stands as a leading company in Healthcare. Generating $447.57 billion in annual revenue (growing 12.3% year-over-year) and carrying a market capitalization of $261.58 billion, the company has cemented its position as a foundational player in the global Healthcare Plans landscape. Under the leadership of its leadership team, UnitedHealth Group Incorporated continues to execute on a multi-year strategic vision that b…
Full UnitedHealth Group analysis →SWOT Analysis Comparison
Strengths
Amgen
- With a market capitalization of $198.16B, Amgen Inc. is one of the largest companies in its sector, providing the scale advantages of brand recognition, supplier leverage, and capital access that smal
- Amgen Inc.'s gross margin of 70.8% is well above industry averages, reflecting pricing power, operational efficiency, or a high-value product mix. The operating margin of 30.5% demonstrates discipline
- A return on equity of 106.1% demonstrates that Amgen Inc. generates strong returns from shareholder capital, a hallmark of companies with durable competitive advantages.
UnitedHealth Group
- With a market capitalization of $261.58B, UnitedHealth Group Incorporated is one of the largest companies in its sector, providing the scale advantages of brand recognition, supplier leverage, and cap
- Revenue grew 12.3% year-over-year to $447.57B, indicating strong demand for UnitedHealth Group Incorporated's products and services and outperformance relative to many industry peers.
- UnitedHealth Group Incorporated generated $13.86B in free cash flow, providing financial flexibility to invest in growth initiatives, return capital to shareholders, or strengthen the balance sheet.
Weaknesses
Amgen
- With a debt-to-equity ratio of 640.3, Amgen Inc. carries significant debt relative to equity. While manageable given its cash flow, elevated leverage limits financial flexibility and increases vulnera
UnitedHealth Group
- UnitedHealth Group Incorporated's debt-to-equity ratio of 81.6 indicates meaningful financial leverage. Total debt stands at $83.00B against $28.12B in cash and equivalents.
- A net profit margin of 2.7% leaves limited buffer against revenue fluctuations or cost increases. Any significant market downturn could quickly pressure profitability.
- With 390,000 employees globally, UnitedHealth Group Incorporated faces inherent challenges in agility, decision-making speed, and maintaining a consistent culture across geographies — advantages that
Opportunities
Amgen
- Amgen Inc. operates in the Drug Manufacturers - General segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in this envi
- Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for Amgen I
- Earnings growth of 112.1% YoY demonstrates Amgen Inc.'s ability to convert revenue growth into shareholder value. Analysts project continued earnings expansion driven by operating leverage as fixed co
UnitedHealth Group
- UnitedHealth Group Incorporated operates in the Healthcare Plans segment of the broader Healthcare sector, which represents a $12 trillion global healthcare market by 2030. Even modest share gains in
- Emerging markets — particularly India (1.4B people, rapidly growing middle class), Southeast Asia (700M people), and Sub-Saharan Africa — represent significant untapped addressable markets for UnitedH
- With $28.12B in cash and strong free cash flow generation, UnitedHealth Group Incorporated is well-positioned to pursue strategic acquisitions that expand its capabilities, customer base, or geographi
Threats
Amgen
- Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. Amgen Inc.'s revenue is not fully insulated from macroeconomic cycles, and a recession scena
- Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on Amgen Inc.'s busine
- Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri
UnitedHealth Group
- Global economic slowdowns, inflation, or rising interest rates can reduce consumer and enterprise spending. UnitedHealth Group Incorporated's revenue is not fully insulated from macroeconomic cycles,
- Increasing government regulation — particularly data privacy laws (GDPR, CCPA), antitrust enforcement, and trade restrictions — poses compliance costs and potential restrictions on UnitedHealth Group
- Competition for skilled technology, engineering, and management talent remains intense. High employee turnover or inability to attract top talent could slow innovation and execution — particularly cri
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Open Comparison ToolAmgen vs UnitedHealth Group: FAQ
- Is Amgen bigger than UnitedHealth Group?
- By market capitalization, UnitedHealth Group is larger at $251.47B vs Amgen's $198.26B.
- Which has better profit margins — Amgen or UnitedHealth Group?
- Amgen has higher net profit margins (21.0%) compared to UnitedHealth Group (2.7%). Gross and operating margins are compared in the table above.
- What sectors do Amgen and UnitedHealth Group operate in?
- Amgen operates in the Healthcare sector (Drug Manufacturers - General). UnitedHealth Group operates in the Healthcare sector (Healthcare Plans).
- How does Amgen's revenue compare to UnitedHealth Group's?
- Amgen generates $36.75B in annual revenue (TTM) while UnitedHealth Group generates $447.57B. UnitedHealth Group is the larger company by revenue as of 2026.